Oncology Competitor Landscapes:
In-line and Pipeline Analysis

Pipeline analysis - Differentiate your pharmaceutical or biotech product within a crowded marketAchieving Differentiation in a Crowded Oncology Market

The First Step Toward a Targeted Approach

Cancer is the most formidable healthcare challenge of our time. The most heavily invested area of drug development is in the search for new agents to treat cancer. There may be hundreds of mutations in every tumor, and determining the ones that drive disease progression is the first step toward a targeted approach. Finding drugs that target the mutations or proteins that arise as a result of them is high priority.

Finding Effective Cancer Therapies

Hallmarks of Cancer – consider implications for oncology competitor pipeline analysis. Contact Pennside Partners for assistance with competitor pipeline and in-line analysis.As Hanahan and Weinberg point out in their famous “Hallmarks of Cancer”[i],  the ability of a drug to interfere with any of these processes resulting in a therapeutic effect  (ie, increased PFS or OS), represents a validation of the hallmark’s capability to promote disease.

Unfortunately each of these hallmarks represents a property with redundant pathways within the cancer cell which ultimately may need to be shut down in order to slow or reverse disease progression.

The ability of cancer cells to adapt to the deleterious effects of agents targeted to specific hallmark processes makes finding effective therapies even more difficult.

So, what does all of this mean for drug developers and why are we discussing it here? 

Each Hallmark an Opportunity for Biotech and Pharma Companies

Each hallmark represents a rich vein of opportunity for biotech and pharma companies to search for effective therapeutics, and indeed, this is exactly what is happening in the world of drug development. There are dozens, if not hundreds of new agents in the pipeline targeted to each of these hallmarks, with more on the way.

It is, therefore, incumbent upon biotech companies who are hoping to win approval of their drugs to understand where their drug will fit into the burgeoning competitive landscape of similar drugs. Not only how they will compete with drugs of similar MOA, but also how they will compete with other kinds of agents seeking to affect any of the hallmark processes. 

Each cancer hallmark represents an opportunity for pharma and biotech companies relative to competing drugs from other pharmaceutical and biotechnology companies. Contact Pennside Partners, a leading pharma and biotech consulting firm for more information.

 



Treatment Algorithms for New Drugs

In addition, as new agents come to market, there is the issue of treatment algorithm: When to use which drug regimen can make or break a promising therapeutic.

The timing of new drug algorithms is critical to proper pipeline analysis when bringing new drugs to market. Contact Pennside Partners, a leading pharma and biotech consulting firm, for assistance with pipeline analysis and related projects.

Understanding How to Position Your Drug

Clinical trial data is the basis of every claim that pharma marketers can make regarding the efficacy of their drugs. It is crucial to understand this data to position your own drug against a background of similar competitors.  

Deep Insight

Pennside’s oncology team can provide deep insight into the complex, rapidly changing landscape of competing MOAs and therapeutic approaches for all tumor types: those on the market now, and those in the pipeline. 


[i] D Hanahan and RA Weinberg, Hallmarks of Cancer: The Next Generation, Cell - 4 March 2011 (Vol. 144, Issue 5, pp. 646-674)


Oncology Consulting and Pipeline Analysis - Learn More

To learn more about our extensive range of consulting services for the pharmaceutical and biotechnology industries, contact Pennside at the office nearest you.

Contact us to learn more about our oncology consulting services for the pharmaceutical and biotechnology industries